cs.AI updates on arXiv.org 09月29日
SurvDiff:生存分析中合成数据生成新模型
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本文提出SurvDiff模型,针对生存分析中合成数据生成问题,通过联合生成混合型协变量、事件时间和右 censoring,优化下游生存任务,提高合成数据的真实性和可靠性。

arXiv:2509.22352v1 Announce Type: cross Abstract: Survival analysis is a cornerstone of clinical research by modeling time-to-event outcomes such as metastasis, disease relapse, or patient death. Unlike standard tabular data, survival data often come with incomplete event information due to dropout, or loss to follow-up. This poses unique challenges for synthetic data generation, where it is crucial for clinical research to faithfully reproduce both the event-time distribution and the censoring mechanism. In this paper, we propose SurvDiff, an end-to-end diffusion model specifically designed for generating synthetic data in survival analysis. SurvDiff is tailored to capture the data-generating mechanism by jointly generating mixed-type covariates, event times, and right-censoring, guided by a survival-tailored loss function. The loss encodes the time-to-event structure and directly optimizes for downstream survival tasks, which ensures that SurvDiff (i) reproduces realistic event-time distributions and (ii) preserves the censoring mechanism. Across multiple datasets, we show that \survdiff consistently outperforms state-of-the-art generative baselines in both distributional fidelity and downstream evaluation metrics across multiple medical datasets. To the best of our knowledge, SurvDiff is the first diffusion model explicitly designed for generating synthetic survival data.

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SurvDiff 生存分析 合成数据生成 临床研究 数据模型
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