A 63-year-old woman showed up at the emergency department of the Brigham and Women’s Hospital in Boston with severe stomach pain, nausea, and vomiting.
She told doctors that for the past month she had developed severe nausea, non-bloody vomiting, and pain she described as a burning feeling that spread from her upper abdomen, through her right side, and around to her back. Nothing she did made it better.
The doctors started collecting her medical history, which was lengthy. The woman had Type 2 diabetes, Stage 2 chronic kidney disease, opioid use disorder, and gastroesophageal reflux disease (GERD), among other conditions. While she was taking many medications, she noted that for the past year she had also been taking semaglutide, a GLP-1 weight-loss drug, and had lost about 40 pounds (over 19 percent of her body weight).
