arXiv:2502.13143v2 Announce Type: replace-cross Abstract: While spatial reasoning has made progress in object localization relationships, it often overlooks object orientation-a key factor in 6-DoF fine-grained manipulation. Traditional pose representations rely on pre-defined frames or templates, limiting generalization and semantic grounding. In this paper, we introduce the concept of semantic orientation, which defines object orientations using natural language in a reference-frame-free manner (e.g., the "plug-in" direction of a USB or the "handle" direction of a cup). To support this, we construct OrienText300K, a large-scale dataset of 3D objects annotated with semantic orientations, and develop PointSO, a general model for zero-shot semantic orientation prediction. By integrating semantic orientation into VLM agents, our SoFar framework enables 6-DoF spatial reasoning and generates robotic actions. Extensive experiments demonstrated the effectiveness and generalization of our SoFar, e.g., zero-shot 48.7% successful rate on Open6DOR and zero-shot 74.9% successful rate on SIMPLER-Env.