All Content from Business Insider 09月20日
CEO因父亲患阿尔茨海默症,调整生活方式以预防认知衰退
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Lifeforce公司CEO Dugal Bain-Kim在父亲被诊断患有阿尔茨海默症后,深刻反思并调整了自己的健康生活方式。他从过去注重力量训练转向更高效的健康管理,包括增加Zone 2有氧运动、优化睡眠、采纳MIND饮食以及考虑微剂量GLP-1药物。他分享了自己对肌酸的积极看法,认为其不仅有助于肌肉增长,还能为大脑提供能量,对抗认知衰退。Bain-Kim的改变源于对家族遗传风险的认知,以及希望通过科学方法积极主动地保护大脑健康,而非被动接受。

🧠 **积极应对认知衰退风险**:在父亲确诊阿尔茨海默症后,CEO Dugal Bain-Kim深刻认识到基因和生活方式对大脑健康的影响。他不再将认知衰退视为无法避免的命运,而是采取了积极主动的措施来保护自己的大脑,包括但不限于关注家族病史和采取科学的预防策略。

💪 **多管齐下的健康策略**:Bain-Kim的健康计划涵盖了多个方面,他不仅坚持力量训练,还大幅增加了Zone 2有氧运动以增强心血管健康,这对大脑功能至关重要。同时,他将睡眠提升到“不可协商”的优先级,认识到高质量睡眠对大脑修复和保护的关键作用。

💊 **审慎选择的营养补充与药物尝试**:在众多健康补充剂中,Bain-Kim仅推荐肌酸,认为其对大脑能量供应和认知保护有益。此外,他正考虑微剂量使用GLP-1类药物,这些药物在管理新陈代谢的同时,也显示出潜在的神经保护作用,反映了他对前沿健康研究的关注和应用。

🍎 **聚焦大脑健康的饮食调整**:Bain-Kim的饮食策略从地中海饮食升级为更侧重于大脑健康的MIND饮食。他强调摄入大量的绿叶蔬菜、坚果、豆类和浆果,以及富含omega-3脂肪酸的鱼类,并以橄榄油作为主要烹饪用油,旨在通过营养素的摄入来支持和保护大脑功能。

Dugal Bain-Kim, CEO of Lifeforce

In his 20s, Dugal Bain-Kim was all about getting swole: lifting big weights, doing long gym sessions, and trying every supplement he could get his hands on.

Now at 41, he has different priorities.

"When I was younger, I had more time to take a spray-and-pray approach to my health and wellness," Bain-Kim, CEO and cofounder of the longevity startup Lifeforce, told Business Insider. "There's enough going on in life to have to be really efficient and really clear about what my most important goals are."

Last year, Bain-Kim had a stark reality check about his health when his father was diagnosed with Alzheimer's disease. His condition deteriorated quickly, and he recently died at age 70.

Knowing his genetic risk, Bain-Kim said he is making some major changes to his routine to protect his brain as much as possible.

"There's this common misperception that Alzheimer's and dementia are like getting struck by lightning, it's just bad luck and there's nothing to do about it," Bain-Kim said. "Having that information can lead someone to think differently about their life."

From microdosing GLP-1 medication to switching up his workouts, here's what he's doing differently that he hopes will move the needle.

Taking creatine: a rising star supplement

While many trendy supplements promise better longevity and brain health, Bain-Kim isn't convinced.

"In general, people are taking too many supplements," he said.

However, he believes one standout exception is creatine, a fitness supplement originally sold for muscle-building that may also protect our brains.

Creatine is a combination of amino acids that our bodies naturally produce to provide energy to tissues like muscle. For years, athletes have used it as a supplement to top up their body's energy reserves to fuel muscle growth.

Emerging research suggests that creatine could have a similar effect on the brain, giving our brain cells extra resources to fend off cognitive decline and stressors like sleep deprivation.

Bain-Kim said he takes creatine daily, alongside protein powder and glutamine (for healthy joints).

Microdosing GLP-1 medication

Blockbuster drugs like semaglutide (sold as Ozempic and Wegovy) and tirzepatide (Mounjaro, Zepbound) are known as GLP-1s. They work on hormone receptors to manage appetite and metabolism.

But growing research suggests that they could have even further-reaching benefits for the brain.

Bain-Kim said he was intrigued by new research that the medications could help stave off cognitive decline. Recent studies have shown GLP-1s like semaglutide and liraglutide are linked to a lower risk of dementia and may slow down the process of brain shrinkage and related thinking problems as we age. More clinical trials are ongoing.

That has inspired Bain-Kim to explore microdosing a GLP-1 himself.

Doing more Zone 2 cardio

The evidence is clear: building a strong body can help protect your brain, too.

Bain-Kim still lifts weights but decided to double down on cardio. A healthy heart and blood flow are essential to keeping the brain functioning well over time.

In particular, exercise like jogging or biking at a lower heart rate (known as Zone 2) can help build a stronger, healthier heart.

Bain-Kim said he's added two sessions a week of light cardio exercise to his routine.

To round out his weekly exercise, he also plays a match of competitive pickleball regularly, as higher-intensity activity helps to boost VO2 max for better fitness and longevity.

Switching to a MIND diet

Bain-Kim said he's optimizing his diet for cognitive health, tweaking his already-healthy Mediterranean diet with even more emphasis on brain-protecting foods.

His new routine is based on the MIND diet, which Harvard researchers developed to help prevent cognitive decline.

It emphasizes nutrients like fiber and healthy fats such as omega-3s that support the brain, through a weekly goal of:

Making sleep a priority

It may not be flashy, but a good night's sleep is the cornerstone of Bain-Kim's daily routine to protect his brain.

He said his personal sweet spot for peak health and performance is about seven hours and 45 minutes of quality sleep, not just time in bed. Neuroscientists recommend between seven and nine hours of sleep.

"Everyone appreciates a good night's sleep, but for me that's now core to my strategy because of the brain protection benefits of getting enough sleep," Bain-Kim said. "It's become the non-negotiable for me."

Read the original article on Business Insider

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认知衰退 阿尔茨海默症 生活方式 健康管理 CEO 肌酸 GLP-1 MIND饮食 Zone 2 Cognitive Decline Alzheimer's Lifestyle Health Management CEO Creatine GLP-1 MIND Diet Zone 2
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