New Yorker 09月05日
新变异株出现,如何应对秋季新冠疫情
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随着新变异株Stratus的出现,美国多地新冠病例激增,尤其在德州和加州。尽管该变异株不一定导致更严重疾病,但其高传播性值得关注。医生建议个人评估自身及身边人群的风险,考虑社区传播情况。若出现症状或接触史,应及时检测,阳性者居家隔离,高风险人群可考虑抗病毒药物。秋季建议接种更新版新冠疫苗及流感疫苗,以增强防护。

🦠 新变异株Stratus的出现预示着新冠疫情的持续演变。该变异株的特点是传播性增强,尽管症状与以往变异株相似,如咳嗽、发烧和疲劳,且“剃刀喉”等极端喉咙痛的报告也有出现,但其高传播性使其成为需要关注的焦点。

⚖️ 个人风险评估是应对当前疫情的关键。应综合考虑自身及家人的健康状况(是否存在易导致重症的潜在疾病),以及所在社区的疫情传播水平。公共卫生部门通过监测废水、住院率和急诊就诊人数等数据,表明许多州的新冠病例正在上升,因此个人应提高警惕。

🏠 出现症状或有接触史的应对措施依然重要。若怀疑感染,应及时进行检测,即使是居家快筛试剂,若结果为阴性,建议两天后再进行一次检测。确诊后应居家隔离,直至发烧消退且症状改善,并在此后几天佩戴高品质口罩(如KN95)。

💉 秋季疫苗接种是重要的防护手段。建议及时接种更新版新冠疫苗,特别是对于老年人或有基础疾病的高风险人群。同时,与流感疫苗一同接种,可以为整个冬季提供更全面的保护,降低感染和重症的风险。

COVID continues to mutate, and a new strain is causing spikes in cases across the country. A conversation with the physician and New Yorker contributor Dhruv Khullar about how we should think about the virus now, and what people can do to protect themselves this fall. Plus:

For many patients, COVID vaccines will be harder to obtain this year.Photograph by Francine Orr / Los Angeles Times / Getty

Daniel A. Gross
A story editor at The New Yorker.

The attacks on mainstream vaccine science and policy in the United States—spearheaded by Robert F. Kennedy, Jr., the Secretary of Health and Human Services—have created a disjointed and confusing public-health landscape ahead of the traditional arrival of flu season. I reached out to Dhruv Khullar, a physician and contributing writer at the magazine who has written extensively about COVID, to talk about some steps that individuals should consider taking this fall. Our conversation has been edited and condensed.

There’s a new variant—called Stratus—that is causing a spike in cases in Texas, California, and beyond. Is that a name that people need to know?

Stratus doesn’t necessarily cause more severe illness than the variants we’ve seen before, and the symptoms are broadly similar—cough, fever, fatigue, and so on. There are some reports of “razor-blade throat,” although that kind of extreme sore throat was seen with prior variants as well. But, by their nature, variants that arise are more transmissible; they’ve outcompeted other variants. From that perspective, they should be on our radar.

People should ask themselves: What is my personal risk, and what is the risk to the people around me? Do I or my loved ones have conditions that would make an infection worse? What is the community spread in my area? Public-health officials look at things like wastewater surveillance, hospitalizations, and emergency-room visits. And the Centers for Disease Control and Prevention estimates that cases are currently rising in more than thirty states.

What do you do if you think you have COVID, or you test positive, in 2025?

These days you’re less likely to end up in the hospital from COVID, but the principles of what to do are not so different from what they were in the past. If you have symptoms or a meaningful exposure—if you spent time in a closed environment with someone who has tested positive—you should test. Over-the-counter rapid tests are not as reliable as P.C.R. tests that you’d get in a doctor’s office, but they’re convenient. If you test negative, then test again two days later.

If you test positive, you should stay home. If you have a condition that puts you at higher risk for serious illness, you could consider taking an antiviral pill like Paxlovid—and the earlier you take it, the better, which is another reason to test. Limit your exposure to other people until you no longer have a fever (even without taking fever-reducing medications such as ibuprofen) and your symptoms are improving. Then you should wear a high-quality mask, such as a KN95, in the days that follow.

Is now the time to get a COVID shot?

The Food and Drug Administration, under Robert F. Kennedy, Jr., approved updated COVID boosters for people over the age of sixty-five, or those with various medical conditions that increase their risk. For everyone else, going forward, it’s going to be more complicated to get the vaccine. If you have the resources and you’re dogged, you can probably still obtain it in most states. A doctor could prescribe shots off-label—but not everyone sees a doctor regularly, and some insurance companies may not cover off-label vaccinations. (The C.D.C. vaccine-advisory panel, which R.F.K., Jr., replaced with new members, will meet in a couple weeks, so guidance could change.)

I think now is the time to get the shot—say, by October or November. Vaccination isn’t a guarantee against infection, or against bad outcomes. But it provides some protection. It’s a good idea to get the COVID vaccine along with the flu vaccine, which should carry you through the winter season.

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新冠病毒 COVID-19 新变异株 Stratus 疫苗接种 公共卫生 疫情防护 COVID-19 New Variant Stratus Vaccination Public Health Pandemic Preparedness
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