In this episode Jack Altman, CEO of Lattice and host of Uncapped, interviews Marc Andreessen on how venture capital is evolving — from small seed funds to billion-dollar barbell strategies — and why today’s most important tech companies don’t just build tools, they replace entire industries. They cover:

The end of “picks and shovels” investingWhy missing a great company matters more than backing a bad oneThe power law math behind fund size and asymmetric returnsAI as the next computing platform — and a test for Western civilizationPreference falsification, media power, and what founders can’t say out loud

This is a conversation about ambition at scale, the structure of modern venture, and the deep forces reshaping startups, innovation, and power.

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